LOINC Italia LOINC®, acronym for Logical Observation Identifiers Names and Codes is an international common language (set of identifiers, names, and codes) for clinical and laboratory observations, which aims at enabling the exchange of diagnostic test results among the IT systems of various healthcare facilities. LOINC was initiated in 1994 by the Regenstrief Institute, a non-profit medical research organization associated with Indiana University (USA), and by the LOINC Committee. Translated into 9 languages and 18 linguistic variants, LOINC is now used in over 150 countries around the world. In accordance with art. 17 of Legislative Decree 69/2013, on 31 March 2014, the Agency for Digital Italy published the Guidelines in order to lay the groundwork for the Electronic Health Record (EHR) regional implementation plans. Both in the EHR and in the Prime Minister’s Decree concerning the EHR, drawn up by the Ministry of Health and to be adopted shortly, the use of LOINC codes for the unique identification of tests is mandatory in medical reports in HL7 CDA2 format. The Institute of Informatics and Telematics (IIT) of the National Research Council (CNR) is the sole partner of the Regenstrief Institute (http://loinc.org/international/italian) and through its LOINC Italia working group (IIT Director’s organizational provision n. 9/201 dated 31/10/2013), is in charge of developing and updating the Italian version of LOINC and of translating the documentation related to it. In order to support users with the implementation and use of LOINC codes, IIT organizes training seminars on the LOINC standard and on the use of the searching and mapping tool RELMA. IIT also offers a Mapping Validity Check service along with continuous assistance regarding both requests for information and specific technical requests through the use of an online helpdesk that can be accessed by clicking here.